背景介紹/context：

The Immortalised Human Neural Stem Cells – L-myc (LM-NSC008) were obtained from fetal brain tissue. After stem cell isolation and propagation, the primary cells were Immortalised by transduction with retrovirus carrying the L-myc gene. The Immortalised Human Neural Stem Cells – L-myc (LM-NSC008) retain the important phenotype of the parental Neural Stem Cells after differentiation such as the expression of neuronal class III b-TUBULIN, astroglial markers SOX9 and GFAP, and oligodendrocyte marker O4, which coincided with neuronal, astrocytic, and oligodendroglial morphologies. The cells show normal karyotype in vitro and did not show abnormal growth or tumorigenicity in vitro. The Immortalised Human Neural Stem Cells – L-myc (LM-NSC008) is a valuable tool for research focusing on CNS diseases.

人永生化神經(jīng)干細(xì)胞L-myc (LM-NSC008)取自胎兒腦組織。原代細(xì)胞經(jīng)分離繁殖后，經(jīng)攜帶L-myc基因的逆轉(zhuǎn)錄病毒轉(zhuǎn)導(dǎo)獲得永生。使人類神經(jīng)干細(xì)胞L-myc (LM-NSC008)保留的重要表型父母的神經(jīng)干細(xì)胞分化后神經(jīng)元的表達(dá)第三類b-TUBULIN等astroglial標(biāo)記SOX9, GFAP和少突細(xì)胞標(biāo)記O4,恰逢神經(jīng)元,星形,oligodendroglial形態(tài)。這些細(xì)胞在體外表現(xiàn)出正常的核型，沒有表現(xiàn)出異常的生長(zhǎng)和致瘤性。永生化的人類神經(jīng)干細(xì)胞L-myc (LM-NSC008)是研究中樞神經(jīng)系統(tǒng)疾病的一個(gè)有價(jià)值的工具。

動(dòng)物種別/Organism  人

組織來源 Tissue and Cell Type 腦組織

形態(tài)/Morphology 貼壁生長(zhǎng) 

注意事項(xiàng)：此產(chǎn)品僅供科研使用