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  • 小鼠永生化小膠質(zhì)細(xì)胞系

小鼠永生化小膠質(zhì)細(xì)胞系

貨號(hào):IM039

價(jià)格: ¥詢價(jià)

規(guī)格:
1*10^6cells
數(shù)量: - +
  • 小鼠永生化小膠質(zhì)細(xì)胞系
產(chǎn)品描述/Products Description

背景介紹/context:

Immortalised microglial cell line (IMG) isolated from the brains of adult mice.Microglia cells share functional similarities with macrophages, and are thought to act as the primary immune cells of the central nervous system (CNS). They monitor their microenviornment and become activated upon detection of abnormal and/or offensive signals. Activated microglia have been found in inflammatory conditions such as brain/spinal cord injury, ischemic strokes, infections and neurodegenerative diseases. Recent findings indicate that microglia are also involved in learning and memory by regulating synaptic plasticity.

從成年小鼠的大腦中分離出的永生化小膠質(zhì)細(xì)胞(IMG)。小膠質(zhì)細(xì)胞與巨噬細(xì)胞在功能上有相似之處,被認(rèn)為是中樞神經(jīng)系統(tǒng)(CNS)的主要免疫細(xì)胞。它們監(jiān)控自己的微環(huán)境,并在發(fā)現(xiàn)異常和/或攻擊性信號(hào)時(shí)被激活。激活的小膠質(zhì)細(xì)胞在炎癥條件下被發(fā)現(xiàn),如腦/脊髓損傷,缺血性中風(fēng),感染和神經(jīng)退行性疾病。最近的研究表明,小膠質(zhì)細(xì)胞也通過調(diào)節(jié)突觸的可塑性參與學(xué)習(xí)和記憶。

動(dòng)物種別/Organism  小鼠

組織來源 Tissue and Cell Type 大腦

形態(tài)/Morphology 貼壁生長(zhǎng) 

 

注意事項(xiàng):此產(chǎn)品僅供科研使用


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