背景介紹/context：

Microglial cell line (SIM-A9) expresses macrophage/microglia specific proteins, CD68 and Iba1.Microglia cells share functional similarities with macrophages, and are thought to act as the primary immune cells of the central nervous system (CNS). They monitor their microenviornment and become activated upon detection of abnormal and/or offensive signals. Activated microglia have been found in inflammatory conditions such as brain/spinal cord injury, ischemic strokes, infections and neurodegenerative diseases. Recent findings indicate that microglia are also involved in learning and memory by regulating synaptic plasticity.

小膠質(zhì)細(xì)胞(si - a9)表達(dá)巨噬細(xì)胞/小膠質(zhì)細(xì)胞特異性蛋白CD68和Iba1。小膠質(zhì)細(xì)胞與巨噬細(xì)胞在功能上有相似之處，被認(rèn)為是中樞神經(jīng)系統(tǒng)(CNS)的主要免疫細(xì)胞。它們監(jiān)控自己的微環(huán)境，并在發(fā)現(xiàn)異常和/或攻擊性信號(hào)時(shí)被激活。激活的小膠質(zhì)細(xì)胞在炎癥條件下被發(fā)現(xiàn)，如腦/脊髓損傷，缺血性中風(fēng)，感染和神經(jīng)退行性疾病。最近的研究表明，小膠質(zhì)細(xì)胞也通過(guò)調(diào)節(jié)突觸的可塑性參與學(xué)習(xí)和記憶。

動(dòng)物種別/Organism  小鼠

組織來(lái)源 Tissue and Cell Type 小膠質(zhì)細(xì)胞

形態(tài)/Morphology 貼壁生長(zhǎng) 

注意事項(xiàng)：此產(chǎn)品僅供科研使用