背景介紹/context：

MLO-A5 cell line is a model for the osteoblast to osteocyte differentiation process, the mineralization process, and the effects of mechanical loading on biomineralization.Derived from a transgenic mouse in which the immortalizing T-antigen was expressed under control of the osteocalcin promoter.Osteocytes are the most abundant bone cells in the body but also the most challenging to study because they are embedded in a mineralized matrix making them to difficult to isolate. This cell line MLO-A5 make it easier to study osteocyte function.

MLO-A5細(xì)胞系是成骨細(xì)胞向骨細(xì)胞分化過程、礦化過程以及機械載荷對生物礦化影響的模型。在骨鈣素啟動子的控制下表達(dá)永生化的t抗原的轉(zhuǎn)基因小鼠。骨細(xì)胞是體內(nèi)最豐富的骨細(xì)胞，但也是最具挑戰(zhàn)性的研究，因為它們嵌入礦化基質(zhì)中，難以分離。MLO-A5細(xì)胞系使骨細(xì)胞功能的研究更加容易。

動物種別/Organism  小鼠

組織來源 Tissue and Cell Type 骨

形態(tài)/Morphology 貼壁生長 

注意事項：此產(chǎn)品僅供科研使用