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產(chǎn)品描述/Products Description
背景介紹/context:
iPSC (induced Pluripotent Stem cells) reprogrammed from human Skin Fibroblasts with Alzheimer-Presenillin-1 Mutation.This iPS cell line was created using a normal human skin fibroblasts generated from a skin biopsy of a patient suffering from Alzheimer. The iPS cell line was generated using an episomal reprogramming containing a prprietary mix of vectors, containing Oct-4, Sox-2, Klf-4 along with p53 Anti-sense, EBNA-1.The cell line was validated for pluripotency based on colony morphology, alkaline phosphatase expression, and expression of SSEA-4.iPS colonies exhibit classical morphology and growth.Absence of Mycoplasma was confirmed.The cell line is shipped on dry ice.
由阿爾茨海默-早老性癡呆-1突變的人類皮膚成纖維細胞重編程的iPSC(誘導多能干細胞)。這種誘導多能干細胞系是用一種正常的人類皮膚成纖維細胞制造的,這些成纖維細胞來自一名老年癡呆癥患者的皮膚活組織切片。iPS細胞系是通過一種非遺傳重編程產(chǎn)生的,其中含有一種彗星載體組合,包括Oct-4, Sox-2, Klf-4和p53 Anti-sense, EBNA-1。根據(jù)菌落形態(tài)、堿性磷酸酶表達和SSEA-4表達驗證該細胞株的多能性。iPS菌落呈現(xiàn)典型的形態(tài)和生長。證實無支原體。細胞系用干冰運送。
動物種別/Organism 人
組織來源 Tissue and Cell Type iPSC(誘導多能干細胞)
形態(tài)/Morphology 貼壁生長
注意事項:此產(chǎn)品僅供科研使用






